Dermatofibroma (DF) also referred to as Benign Fibrous Histiocytoma, is a very common skin lesion, described as usually a single round or ovoid papule or nodule, about 0.5 to 1.0 cm in diameter, often reddish brown but sometimes has a yellowish hue Definition / general Dermatofibromas (also known as fibrous histiocytomas) are a spectrum of benign dermal based lesions with fibroblastic and histiocytic differentiation There is debate as to whether dermatofibroma is a reactive or neoplastic proces . It is benign (harmless) and will not turn into a cancer. Whilst dermatofibromas are harmless, they can be similar in appearance to other concerning skin tumours. It is therefore im
A dermatofibroma is a common benign fibrous nodule usually found on the skin of the lower legs. A dermatofibroma is also called a cutaneous fibrous histiocytoma. Who gets a dermatofibroma? Dermatofibromas are mostly seen in adults Dermatofibroma is a common benign tumour also known as fibrous histiocytoma. There is debate as to whether dermatofibroma has a reactive or neoplastic origin. The clinical lesion is a firm tan-brown nodule most commonly found on the legs. A number of histological variants exist
Gershtenson, PC, Krunic, A, Chen, HM. Multiple clustered dermatofibroma: case report and review of the literature. J Cutan Pathol. vol. 37. 2010. pp. e42-e45. (A review of the implications of the occurrence of multiple dermatofibromas.) Gonzales, S, Duarte, I. Benign fibrous histiocytoma of the skin. A morphologic study of 290 cases By Rodney T. Miller, M.D., Director of Immunohistochemistry Although many times the distinction of dermatofibroma (a.k.a. fibrous histiocytoma) (DF-FH) from dermatofibrosarcoma protuberans (DFSP) is relatively easy to make on H&E, in some cases it can be difficult. Obviously, accurate diagnosis is important, since the natural history and treatment of DFSP differs greatly from that of DF-FH Dermatofibromas may also be called benign fibrous histiocytomas. Causes and risk factors Dermatofibromas are an accumulation of extra cells within the deeper layers of the skin. The exact cause of.. Terminology. First described in 1981 ( Cancer 1981;47:2053 ) Early lesion also called hemosiderin variant of fibrous histiocytoma. Similar to sclerosing hemangioma variant of fibrous histiocytoma, which has more prominent capillaries, but differs from lung lesion called sclerosing hemangioma Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma
Dermatofibroma (superficial benign fibrous histiocytoma) is a common cutaneous nodule of unknown etiology that occurs more often in women. Dermatofibroma frequently develops on the extremities.. Thirty-four cases of fibrous histiocytoma (dermatofibroma) arising on the face are reported. These neoplasms occurred frequently in females (24 female, 10 male) and showed a broad age range (12 to 85 years; mean: 43.6 years, median: 41 years) Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) are dermal tumors whose histogenesis has not been well defined to date. The differential diagnosis in most cases is established in routine H/E sections and may be confirmed by immunohistochemistry, but there are atypical variants of DF with less clear histological differences and non-conclusive immunohistochemical results An atrophic dermatofibroma—a variant of a dermatofibroma—is an uncommon benign fibrohistiocytic tumor that usually presents in adults as an asymptomatic depressed plaque [1,2,3,4].A comprehensive review of the literature was performed using the PubMed database to search the words: atrophic dermatofibroma; the relevant papers and their references generated by the search were reviewed
Aneurysmal benign fibrous histiocytomas are variants of dermatofibromas. These benign blood‐filled lesions can mimic malignancies due to their rapid and recurrent growth. Our patient is a 42‐year‐old Caucasian female with a past medical history of morbid obesity, diabetes, and hypertension, who presented with a mass on her left shoulder. Dermatofibroma (fibrous histiocytoma) represents a frequent benign mesenchymal neoplasm of the skin, which rarely may also occur in subcutaneous and deep soft tissues. 1 Over the years, several.
Dermatofibroma, otherwise known as benign fibrous histiocytomas, dermal dendrocytoma, Fibrous dermatofibroma, Fibrous histiocytoma, Nodular subepidermal fibrosis, and Sclerosing hemangioma, is a skin growth, considered benign.It is found mainly on the legs and can grow up to 1cm in diameter. The condition primarily consists of fibrous tissue or scar like tissue under the skin Dermatofibroma (DF) is a common benign skin tumor (Benign Fibrous Histiocytoma) that mostly affects the ex-tremities more than any other site in the body with a ten-dency to occur more in older females than males.1 It usually presents as a slow growing small (<2cm) brown dome shape papule on the extremities2 compression on both side
A dermatofibroma, or benign fibrous histiocytomas, is a benign skin growth .6 It is a variant of cutaneous histiocytoma or dermatofibroma described by Fletcher in 1990 as a tumor originating in the subcutaneous tissue [2-5] Dermatofibroma, also referred as benign fibrous histiocytoma, is a relatively common noncancerous cutaneous nodule. Males are less affected by dermatofibroma than females, with a female-to-male ratio of 4:1. The exact etiology for the development its development is still undetermined. This condition appears more likely to be a neoplastic. Dermatofibroma (Benign Fibrous Histiocytoma) David S. Cassarino, MD, PhD Key Facts Terminology Benign limited proliferation of histiocytic and fibroblastic cells in dermis Etiology/Pathogenesis Evidence supports both neoplastic and reactive pathogenesis Clinical Issues Affects all ages and both sexes but most common in young adults Excellent prognosis in vast majority of cases Metastasis and.
BACKGROUND: Dermatofibroma (DF) is a superficial form of benign fibrous histiocytoma, composed of a mixture of fibroblastic cells and histiocytic cells. The histogenesis of this lesion is a matter of controversy. METHODS: Forty-five cases of DF were investigated by single and multiple immunostaining techniques, using panel of 12 antibodies. Benign Fibrous Histiocytoma is a rare tumor of mesenchymal origin. First described in 1958 by Dahlin. They are composed of two cell types, namely atypical fibroblasts and histiocytes, arranged in a storiform pattern. Lipid-filled cells may be conspicuous and occasionally are the major component Aneursymal variant of benign fibrous histiocytoma: no thick pseudocapsule, no inflammatory cells, no significant pleomorphism Angiosarcoma: endothelial tufting present, CD31+, CD34+, desmin- Additional references. Arch Pathol Lab Med 2008;132:273, Atlas of Genetics and Cytogenetics, Stanford University
Benign Fibrous Histiocytoma: A benign tumor composed, wholly or in part, of cells with the morphologic characteristics of HISTIOCYTES and with various fibroblastic components. Fibrous histiocytomas can occur anywhere in the body. When they occur in the skin, they are called dermatofibromas or sclerosing hemangiomas. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 5th ed, p1747 INTRODUCTION. Fibrous histiocytomas are divided into two subgroups: malignant and benign fibrous histiocytomas (BFHs). BFH is one of the most common tumors of the superficial and deep soft tissues; it is commonly found on the skin and presents as a slow-growing solitary nodule made up of a mixture of fibroblastic and histiocytic cells Microscopically, aneurysmal fibrous histiocytoma can be difficult to identify, as the lesion will display some similarities to a classic dermatofibroma along with distinguishing characteristics, like large blood-filled cavernous spaces. Aneurysmal fibrous histiocytoma is a benign lesion with a low risk for recurrence if adequately excised Dermatofibroma is a condition wherein benign growths develop on the skin tissue. These growths are tender to the touch and appear singularly or in groups and linger for long periods of time. The fibrous skin growths sometimes occur right where an insect bite is found. They commonly appear on the arms and legs
Benign fibrous histiocytomas (also known as Dermal dendrocytoma, Dermatofibroma, Fibrous dermatofibroma, Fibrous histiocytoma, Fibroma simplex, Nodular subepidermal fibrosis, and Sclerosing hemangioma) are benign skin growths Calonje E. Is cutaneous benign fibrous histiocytoma (dermatofibroma) a reactive inflammatory process or a neoplasm? Histopathology 2000;37(3):278-80. doi: 10.1046/j.1365-2559.2000.00986.x. Search PubMed; Vanni R, Fletcher CD, Sciot R, et al. Cytogenetic evidence of clonality in cutaneous benign fibrous histiocytomas: A report of the CHAMP.
Aneurysmal benign fibrous histiocytomas are variants of dermatofibromas. These benign blood‐filled lesions can mimic malignancies due to their rapid and recurrent growth. Our patient is a 42‐year‐old Caucasian female with a past medical history of morbid obesity, diabetes, and hypertension, who presented with a mass on her left shoulder for 5 years' duration . K. Swer1 *, 1 Lecturer, Dept. of Shalya tantra, North East Institute of Ayurveda and Homeopathy, Shillong, India Abstract Background: Dermatofibroma or Benign fibrous histiocytoma is a benign skin growth
^ benign fibrous histiocytoma at Dorland's Medical Dictionary ^ Dermatofibroma | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program. rarediseases.info.nih.gov. Retrieved 2018-04-17. ^ dermatofibroma at Dorland's Medical Dictionary ^ a b c Dermatofibroma at eMedicin INTRODUCTION Dermatofibroma is also known as a fibrous histiocytoma. It is a common benign cutaneous tumor of unknown etiology that is more common in females. Although these tumors occur most commonly on the extremities, they have also been described on the eyelids aneurysmal benign fibrous histiocytoma A distinct variant of benign fibrous histiocytoma (BFH) characterised by slow growing nodules with central cystic haemorrhage that imparts a blue-brown colour, which may result in clinical misdiagnosis as melanoma or a vascular lesion. Rapid growth and pain have been described in aneurysmal BFH
All cases coded as dermatofibroma, sclerosing hemangioma, histiocytoma, fibrous histiocytoma, or subepidermal nodular fibrosis in the files of the Division of the Surgical Pathology, Barnes Hospital, St. Louis, Missouri, were reviewed for the years 1971 to 1977. Cases with the histologic pattern of fibrous histiocy Define benign fibrous histiocytoma. benign fibrous histiocytoma synonyms, benign fibrous histiocytoma pronunciation, benign fibrous histiocytoma translation, English dictionary definition of benign fibrous histiocytoma. dermatofibroma. Translations. English: der·ma·to·fi·bro·ma n. tumor benigno de la piel de crecimiento lento Dermatofibroma (Histiocytoma; Benign Fibrous Histiocytoma) Pronounced: der-MAH-toe-fie-BRO-ma. by ]]> Diane Safer, PhD]]> Definition. A dermatofibroma is extremely common. It is a small, firm bump on the skin. The bump is an overgrowth of the tissue lying between the outer and inner layers of skin. The bump is generally pinkish-brown in color.
Dermatofibroma and Fibrous Histiocytoma David Cassarino, MD, PhD Key Facts Terminology Benign, limited proliferation of histiocytic and fibroblastic cells in dermis Etiology/Pathogenesis Evidence supports both neoplastic and reactive pathogenesis Clinical Issues Affects all ages, but most common in young adults Excellent prognosis in vast majority of cases Metastasis and death in rare cases of. and benign fibrous histiocytoma to be separate conditions and report differences in recurrence rates between them. Published in the Journal of Dermatology in 2005, they consider dermatofibroma to have a much lower recurrence rate than benign fibrous histiocytoma. Authors reporting these differences also describe that benign fibrous histio . DF occurs anywhere on the body surface but has a propensity for the extremities. To our knowledge, DF arising in th Benign fibrous histiocytoma, Dermatofibroma, Pain INTRODUCTION Based on location, benign fibrous histiocytomas (BFH) are classified into cutaneous and deep tissue subtypes. Cutaneous BFH are common, while deep-seated BFH are rare and painful, deep-seated dermatofibroma is even more rarely reported. When BFH is deep-seated and associated with.
Fibrous histiocytoma (FH) or dermatofibroma is a common cutaneous lesion mostly seen in adults and rare in the first two years of life. Two hundred sixty-seven patients younger than 18 years with a diagnosis of FH or dermatomyofibroma, a lesion with morphologic overlap with FH, were identified from the files of a single institution, with only 13 (4.8%) occurring in patients younger than 5 years Atypical Fibrous Histiocytoma of the cheek and Atypical Fibroxanthoma of the ear. DISCUSSION. These two cases represent different parts of the spectrum of benign mesenchymal spindle cell tumors. The woman's cheek diagnosis was upgraded to atypical fibrous histiocytoma (AFH) bordering on an atypical fibroxanthoma (AFX) after tumor excision
INTRODUCTION. Dermatofibroma, also known as fibrous histiocytoma, is one of the most common cutaneous soft-tissue lesions, accounting for approximately 3% of skin lesion specimens received by dermatopathology laboratories. 1 If the classical clinical and pathologic features are present the diagnosis is usually straightforward. However, in the presence of a variant diagnosis can be challenging Benign dermatofibroma is a very common skin tumor and may recur. However, metastasis of dermatofibroma is a very uncommon event , , .To the best of our knowledge, 12 cases were reported in the English literature since the first description by Joseph et al in 1990. On the observations of previous published cases, the tumors occur in young male adults and present as multiple cavitary or cystic. Dermatofibroma. Image courtesy of Marie Schreiner, PA-C. Dermatofibromas are common among adults, more so in women. Their cause is probably genetic. Lesions are usually 0.5 to 1 cm in diameter, firm, and may dimple inward with gentle pinching. Most lesions are asymptomatic, but some itch or ulcerate after minor trauma Dermatofibromas are common benign fibrohistiocytic lesions, usually appearing as slow growing firm dermal nodules with a predilection for the extremities (mostly the lower legs). They are found mostly in middle-aged women and are usually smaller than 2 cm in diameter. Giant dermatofibromas exceeding 5 cm in diameter are rare. In recent years, reports have suggested a relationship between the. Best answers. 0. Jun 27, 2018. #1. Wondering what other coder's opinions are on whether to choose 88304 or 88305 for the pathology of a dermatofibroma. Lipomas and soft tissue tumors are clearly marked as being 88304, but that is soft tissue. Dermatofibroma are benign skin tumors
Benign fibrous histiocytoma (dermatofibroma) of the face: clinicopathologic and immunohistochemical study of 34 cases associated with an aggressive clinical course. The American journal of dermatopathology , 23 (5), 419-426 Benign fibrous histiocytoma of bone. Dr Daniel J Bell and Dr David Dang et al. Benign fibrous histiocytoma is closely related to fibroxanthoma of bone , is a rare lesion usually occurring in the skin where it is known as dermatofibroma. On this page . When located superficially in the skin, they are referred to as dermatofibroma. They appear as slow-growing nodules in adults, often involving the extremities
Dermatofibroma. INTRODUCTION Dermatofibroma is also known as a fibrous histiocytoma. It is a common benign cutaneous tumor of unknown etiology that is more common in females. Although these tumors occur most commonly on the extremities, they have also been described on the eyelids. These lesions represent multiple variants of tumors derived. Dermatofibroma is a common red or brown benign skin tumor. They often form on the legs in response to an injury like an insect bite or a splinter. Dermatofibroma has also been referred to as a fibrous histiocytoma. Dermatofibromas are hard, round growths that are visible above the skin, but they extend down into the deeper layers of skin as well
Dermatofibroma (DF) or cutaneous fibrous histiocytoma is a common benign skin tumor that exhibits multiple, distinct histologic variants. Although clear cell DF has been described in the literature, balloon cell degeneration causing a clear cell DF phenotype has been not been reported to date Cutaneous Fibrous Histiocytoma Definition (NCI) A solitary, slowly growing nodular mass, most often affecting the extremities. It is composed of fibrous and histiocytic cells which infiltrate the dermis and occasionally the underlying subcutaneous tissue. Usually local excision is curative Sir, Dermatofibroma is one of the most common mesenchymal growths of the skin  which is also known as cutaneous fibrous histiocytoma. Clinical presentation is typically a solitary, slowly growing reddish-brown nodule that arises from the dermis, associated with epidermal changes. It usually develops in young adulthood. Although the precise etiopathogenesis is still unknown, injuries to the.
Epithelioid fibrous histiocytoma (EFH) is a rare lesion believed to arise from dermal microvascular unit fibroblasts and dendritic histiocytes. EFH has long been considered a morphologic variant of benign fibrous histiocytoma (dermatofibroma), with prominent epithelioid cytomorphology that can mimic both vascular and melanocytic neoplasms Aneurysmal dermatofibroma is a rare variant of cutaneous fibrous histiocytoma (dermatofibroma) thought to be secondary to slow extravasation of blood into the lesion. The resulting entities have different clinical and pathological presentations that can lead to diagnostic confusion with other types of skin lesions. We discuss the defining features of aneurysmal dermatofibroma to outline. Dermatofibroma NOS, [M]Dermatofibroma NOS, Dermatofibroma (disorder), Dermatofibroma, no ICD-O subtype, dermatofibromas, sclerosing hemangioma, cutaneous histiocytoma, histiocytomas, pleomorphic fibroma, histiocytoma, Pleomorphic fibroma, Pleomorphic fibroma (disorder), Subepidermal nodular fibrosis, Cutaneous histiocytoma (disorder), Fibrous. A benign tumor composed, wholly or in part, of cells with the morphologic characteristics of HISTIOCYTES and with various fibroblastic components. Fibrous histiocytomas can occur anywhere in the body. When they occur in the skin, they are called dermatofibromas or sclerosing hemangiomas AFH is also known as dermatofibroma with monster cells (2) or atypical benign fibrous histiocytoma (3). This neoplasm is characterized by a relatively benign clinical course despite having pseudosarcomatous histological features (1-3); however, in comparison with FH, recurrence of AFH is common, although metastases are rare (4)